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PGY2 Critical Care

The PGY2 Critical Care Residency program at Maine Medical Center offers residents quality training in a pharmacy-friendly institution where resident learning is of utmost importance. Maine Medical Center is a welcoming environment that appreciates work-life balance and is supportive of the resident and their experience. We are dedicated to the care of our patients.

As Maine’s only Level 1 Trauma Center and a comprehensive stroke center, our residents see a diverse array of pathology. Our pharmacists have 24/7 coverage in the emergency department. Pharmacists are key members of the multidisciplinary teams in our ICUs. Our providers expect us to be on rounds and are hunting us down if we are not!

Our faculty is comprised of a tight-knit group of well-respected and accomplished preceptors. Faculty work closely with colleagues from every discipline which is highlighted by our multidisciplinary research efforts and our residency advisory committee, consisting of pharmacists, nurses, physicians, and advanced practice providers. Learn more about our faculty.

Our program supports our resident’s desire to be involved in quality improvement projects as well as research. Our strong research mentorship with established clinical researchers and aspiring researchers often leads to publications (on average 5-10 per year in an interdisciplinary fashion). Learn more about our research projects.

Located in beautiful Portland, Maine, our setting provides an added bonus to the resident experience at Maine Medical Center. Maine is called “vacationland” for a reason - Lonely Planet and Fodor’s have given shout-outs to Maine as one of the best places to visit in the world. Having easy access to a range of outdoor activities and top-notch food and beer establishments to quench our foodie palates allows residents to enjoy life outside of work.

From start to finish, our staff is dedicated to our resident’s progression and ensuring they have the training and experience necessary to graduate to a competitive position. Learn more about our alumni.

Below are some examples of recent PGY2 Critical Care Pharmacy Residency research projects:

  • Phenobarbital-based Protocol for Trauma Patients at High Risk of or Experiencing Alcohol Withdrawal – retrospective before-and-after
  • Acute Pain Management in Patients with Opioid Use Disorder Requiring Critical Care – narrative review
  • Risk Factors for an Elevated Free Fraction of Valproate in Critically Ill Adults – two-center retrospective cohort
  • Methadone Bioavailability and Dose Conversion Implications with Intravenous and Enteral Administration – scoping review
  • Evaluation of Enteral Phosphate Replacement in the Intensive Care Unit – retrospective cohort
  • Non-Opioid Analgesics in the Intensive Care Unit – narrative review
  • Intensive Care Analgesic Review and Opioid Use Disorder – retrospective cohort
  • Accuracy of Point-of-Care Blood Glucose Levels in Critically Ill Patients with Sepsis Receiving High-Dose Vitamin C – prospective observational pilot
  • Opioid Rotation from Fentanyl to Hydromorphone – prospective observational
  • Neurostimulants in Acute Stroke Patients – retrospective cohort
  • Cefepime-induced Neurotoxicity - systematic review
  • Phenobarbital for Agitation in the Intensive Care Unit – retrospective cohort

MMC PHARMACY RESIDENT PUBLICATIONS 2016-2020 (Bold = PGY2 Resident authors, italic = preceptor)

  • Liu J, Smith KE, Riker RR, Craig WY, McKelvy DJ, Kemp HD, Nichols SD, Fraser GL. Am J Health-Syst Pharm 2021;78:1395-1401.
  • Wampole CR, Smith KE. Beyond Opioids for Pain Management in Adult Critically Ill Patients. J Pharm Pract 2019;32:256-70. doi: 10.1177/0897190019834479.
  • Kovacic N, Gagnon DJ, Riker RR, Fraser GL. An analysis of psychoactive medications initiated in the ICU but continued beyond discharge: a pilot study of stewardship. J Pharm Pract 2019 [Epub ahead of print].
  • Brown CS, Zemrak WR, Dyer KJ, Rolfe S. Low-Dose Prothrombin Complex Concentrate in Patients with Left Ventricular Assist Devices. ASAIO J 2019;65:e21-e24.
  • Smith KE, Brown CS, Manning BM, et al. Accuracy of point-of-care blood glucose level measurements in critically ill patients with sepsis receiving high-dose intravenous vitamin C. Pharmacotherapy 2018; 38:1155-1161.
  • Payne LE, Gagnon DR, Riker RR, Seder DR, Glisic EK, Morris JG, Fraser GL. Cefepime-Induced Neurotoxicity: A Systematic Review. Crit Care 2017; 21:276.
  • Zemrak WR, Kelley E, Kovacic NL, Mooney DM, Morris JG, MacVane C, Rosenblatt JA. Thrombotic complications following the administration of high-dose prothrombin complex concentrate for acute warfarin reversal. Am J Emerg Med 2016;34:1736.e1-3.
  • Payne LE, Fraser GL. Power Pak C.E. A review of pharmacotherapy management of pain, agitation, and delirium in adult patients in the ICU. 2016.

Our curriculum is deeply rooted in foundational experiences within critical care with many unique opportunities to experience a wide range of specialty areas. Every year our curriculum is customized to the interests and needs of the resident. The program director and preceptors will work with the resident to optimize and adjust the program and learning experiences. Please refer to our manual for more information on learning experiences. View PGY2 Critical Care Pharmacy Appendix.


Learn more about application requirements, stipends & benefits.


Kathryn Smith, PharmD, BCPS, BCCCPLearn more about our Program Director, Kathryn Smith, PharmD, BCPS, BCCCP.